Search results for "Chloride-Bicarbonate Antiporters"

showing 2 items of 2 documents

Bowel Dilation Diagnosed Prenatally.

2017

AdultDiarrheamedicine.medical_specialtyCongenital chloride diarrheaColonMEDLINEPrenatal diagnosisGestational AgeConservative TreatmentUltrasonography Prenatal03 medical and health sciences0302 clinical medicinePregnancy030225 pediatricsPrenatal DiagnosismedicineHumansChloride-Bicarbonate AntiportersPregnancy030219 obstetrics & reproductive medicinebusiness.industryObstetricsCesarean SectionFollow up studiesInfant NewbornPregnancy OutcomeGestational ageGene Expression Regulation Developmentalmedicine.diseaseDilatationMagnetic Resonance ImagingSulfate TransportersPediatrics Perinatology and Child HealthFemaleUltrasonographybusinessBowel dilationMetabolism Inborn ErrorsFollow-Up StudiesThe Journal of pediatrics
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The CFTR associated protein CAP70 interacts with the apical Cl-/HCO3- exchanger DRA in rabbit small intestinal mucosa.

2005

DRA (down regulated in adenoma) is an intestinal anion exchanger, acting in parallel with NHE3 to facilitate ileal and colonic NaCl absorption. Furthermore it is involved in small intestinal bicarbonate secretion. Because DRA has a PDZ interaction motif, which may influence its properties, we searched for DRA-interacting PDZ adapter proteins in the small intestine. Using an overlay assay with the recombinant DRA C-terminus as a ligand, a 70 kDa protein was labeled, which was restricted to the brush border membrane in rabbit duodenal and ileal mucosa and was not detected in the colon. Destruction of the C-terminal PDZ interaction motif abolished this band, suggesting a specific protein-prote…

Brush borderColonPDZ domainAmino Acid MotifsMolecular Sequence DataCystic Fibrosis Transmembrane Conductance RegulatorIleumBiologyBiochemistryAntiportersCell LineIntestine SmallmedicineAnimalsHumansSecretionAmino Acid SequenceChloride-Bicarbonate AntiportersRNA MessengerIntestinal MucosaMessenger RNAHEK 293 cellsSignal transducing adaptor proteinMembrane ProteinsMolecular biologySmall intestinePeptide Fragmentsmedicine.anatomical_structureSulfate TransportersRabbitsCarrier ProteinsBiochemistry
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